@Article{AntoniniMSTVSCMM:2019:OsDiBo,
author = "Antonini, Leonardo Marasca and Menezes, Tiago Lemes and Santos
J{\'u}nior, Adilar Gon{\c{c}}alves dos and Takimi, Antonio
Shigueaki and Villarinho, Denis Jardim and Santos, Bruno Paiva dos
and Camassola, Melissa and Marcuzzo, Jossano Saldanha and
Malfatti, C{\'e}lia de Fraga",
affiliation = "{Universidade Federal do Rio Grande do Sul (UFRGS)} and
{Universidade Federal do Rio Grande do Sul (UFRGS)} and
{Universidade Federal do Rio Grande do Sul (UFRGS)} and
{Universidade Federal do Rio Grande do Sul (UFRGS)} and
{Universidade Feevale} and {University of Bordeaux} and
{Universidade Luterana do Brasil} and {Instituto Nacional de
Pesquisas Espaciais (INPE)} and {Universidade Federal do Rio
Grande do Sul (UFRGS)}",
title = "Osteogenic differentiation of bone marrow-derived mesenchymal stem
cells on anodized niobium surface",
journal = "Journal of Materials Science: Materials in Medicine",
year = "2019",
volume = "30",
number = "9",
pages = "e104",
month = "Sept.",
abstract = "Currently, titanium and its alloys are the most used materials for
biomedical applications. However, because of the high costs of
these metals, new materials, such as niobium, have been
researched. Niobium appears as a promising material due to its
biocompatibility, and excellent corrosion resistance. In this
work, anodized niobium samples were produced and characterized.
Their capacity to support the osteogenic differentiation of bone
marrow-derived mesenchymal stem cells (BM-MSCs) was also tested.
The anodized niobium samples were characterized by SEM,
profilometry, XPS, and wettability. BM-MSCs were cultured on the
samples during 14 days, and tested for cell adhesion, metabolic
activity, alkaline phosphatase activity, and mineralization.
Results demonstrated that anodization promotes the formation of a
hydrophilic nanoporous oxide layer on the Nb surface, which can
contribute to the increase in the metabolic activity, and in
osteogenic differentiation of BM-MSCs, as well as to the
extracellular matrix mineralization.",
doi = "10.1007/s10856-019-6305-z",
url = "http://dx.doi.org/10.1007/s10856-019-6305-z",
issn = "0957-4530",
language = "en",
targetfile = "Antonini2019_Article_OsteogenicDifferentiationOfBon.pdf",
urlaccessdate = "27 abr. 2024"
}